March 26, 20263 min read

Half-Life Calculator — Radioactive Decay and First-Order Reactions

Calculate radioactive decay, remaining quantity, or elapsed time using half-life. Works for nuclear decay, drug elimination, and any first-order decay process.

half-life radioactive decay first order kinetics calculator calchub
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Half-life is one of the most intuitive concepts in all of science: the time it takes for half of something to disappear. It shows up in nuclear physics (radioactive decay), pharmacology (drug elimination), and chemistry (first-order reactions). The CalcHub Half-Life Calculator solves for any unknown — remaining quantity, elapsed time, or half-life itself — given the other two values.

The Key Equations

For a first-order decay process:

N(t) = N₀ × (1/2)^(t/t½)

Which is equivalent to:

N(t) = N₀ × e^(−λt), where λ = ln(2)/t½

VariableMeaning
N₀Initial quantity
N(t)Remaining quantity at time t
tElapsed time
Half-life
λDecay constant

How to Use the Calculator

  1. Open CalcHub and go to the Half-Life Calculator.
  2. Enter any two of: initial quantity, remaining quantity, elapsed time, and half-life.
  3. The tool solves for the missing variable.
  4. Quantity can be in grams, atoms, moles, Becquerels, or any proportional unit.

Worked Examples

How much of a 100 g sample of C-14 remains after 11,460 years? (t½ = 5,730 years)

N(t) = 100 × (1/2)^(11460/5730) = 100 × (1/2)² = 100 × 0.25 = 25 g

(Exactly 2 half-lives → one quarter remains.)

A drug has a half-life of 4 hours. After how long will 90% be eliminated?

Remaining = 10%, so N(t)/N₀ = 0.10
0.10 = (1/2)^(t/4)
ln(0.10) = (t/4) × ln(0.5)
t = 4 × ln(0.10)/ln(0.5) = 4 × 3.322 = 13.3 hours

Half-Lives of Common Isotopes

IsotopeHalf-LifeApplication
Carbon-14 (¹⁴C)5,730 yearsArchaeological dating
Uranium-238 (²³⁸U)4.47 × 10⁹ yearsGeological dating
Iodine-131 (¹³¹I)8.02 daysThyroid treatment
Technetium-99m (⁹⁹ᵐTc)6.01 hoursMedical imaging
Radon-222 (²²²Rn)3.82 daysEnvironmental hazard
Fluorine-18 (¹⁸F)110 minutesPET scanning

Multiple Half-Lives at a Glance

Half-lives elapsedFraction remaining% remaining
11/250%
21/425%
31/812.5%
51/323.1%
101/10240.1%

Why is radioactive decay always first-order?

Because the probability that any single nucleus decays in a given time interval is constant and independent of all other nuclei. This is the statistical definition of a first-order process. No matter how many atoms you have, a fixed fraction decays per unit time.

Does half-life change with temperature or pressure?

For chemical reactions, yes — half-life depends on temperature through the rate constant. For nuclear decay, no — radioactive half-lives are completely unaffected by temperature, pressure, or chemical environment. That's what makes them reliable as geological and archaeological clocks.

What is carbon dating and how does it use half-life?

Living organisms continuously exchange carbon with the atmosphere, maintaining a roughly constant ratio of ¹⁴C to ¹²C. When an organism dies, the ¹⁴C decays without replenishment. Measuring the remaining ¹⁴C ratio and knowing the half-life (5,730 years) lets you calculate time of death — accurate to about 50,000 years back.


Related calculators: Rate of Reaction Calculator · Electrochemistry Calculator · Percent Yield Calculator
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